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Hyaluronic Acid Application

2019-04-09

Food supplements:
Hyaluronan through oral administration can increase the precursor of hyaluronan synthesis in vivo after the digestion and absorption, which will promote the generation of hyaluronan in the skin and other tissues and thus enable the skin to increase its water retention property, improve its elasticity and reduce wrinkles.

Medical applications:
Hyaluronan could be used in eye surgery, such as corneal transplantation, cataract surgery, glaucoma surgery, and retinal detachment repair.

Hyaluronan can also be used to treat osteoarthritis of the knee. It is injected into the knee joint to supplement the viscosity of the joint fluid, thereby lubricate the joint, cushion the joint and produce an analgesic effect.

Hyaluronan has also been used in the synthesis of biological scaffolds for wound-healing applications. These scaffolds typically have proteins such as fibronectin attached to the hyaluronan to facilitate the cell migration into the wound.

Hyaluronan is also used in anti-adhesive products, which are widely used in pelvic and abdominal surgery to prevent postoperative adhesions.

Cosmetics applications:
Hyaluronan has outstanding moisture keeping ability, thus is called natural moisturing factor in the world. It can be used as an effective topical humectant and is a common ingredient in skin-care products.

In 2003, the FDA approved hyaluronan injections for filling soft tissue defects and they can be adopted in folds and wrinkles reduction, lip augmentation and scars removal.

Equine applications:

Hyaluronan is used in treatment of articular disorders in horses such as carpal and fetlock joint dysfunction, synoyitis and equine osteoarthritis, in particular for racing horses or work horses. It can be injected directly into an affected joint, or intravenously for less localized disorders. It may cause mild heating of the joint if directly injected, but that does not affect the clinical outcome. Intra-articular administered medicine can be fully metabolized within a week.

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