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Sodium Hyaluronate Medium Molecular Weight Grade for Eye Drops
HA can improve the ocular bioavailability of the drug by increasing the viscosity of solution and prolonging the time of the drug in the eye, relieve drug stimulation, increase eye drops lubrication and comfort. Ha has excellent biotolerability with ocular tissue, and can be used in many kinds of eye drops.
Hyaluronic acid is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints. The hyaluronic acid that is used as medicine is extracted from rooster combs or made by bacteria in the laboratory.
(1)It can protect corneal endothelial in surgery, epithelium, iris and retina.
(2)It can be instead of aqueous humor without loss, so it can keep the depth of anterior chamber during the surgery.
(3)It is injected into glass cavity ,helping to reset the retina because of oppression.
(4)It can enter the conjunctiva under the pillow to keep filter pillow uplift in glaucoma surgery.
(5) It can help to reduce the adhesion for separation tissue surface.
1.Topical (eye drop) can sometimes have a thrill, foreign body sensation, itching, reddening, diffuse surface keratitis, etc. After eye surgery, this drug with blood or residual crystals mixing in the eye , can delay absorption and inflammation, and short elevated intraocular pressure. Local injection can have a sexual pain swelling or fever. Possible allergies are: sometimes may be blepharitis, eyelid skin inflammation, individual patients can also be a skin rash, itching, rare shock, urticaria, etc.
2. [contraindications]Allergies to this medicine , venous and lymphatic return leg disorders, patients with knee infection or inflammation, Articular cavity infection of acute phase to disable the articular cavity injection. To diabetic patients with no crystal, tis ban to the use of this drug in large quantities in surgery.
3. Caution:Allergies to the drugs, liver dysfunction or a history of liver function obstacle, the elderly, children, pregnancy, nursing mothers.
4. The use of this drug in the operation should be avoiding excessive packing. After the surgery with a balanced salt solution according to the need to remove residual liquid, this can control the intraocular pressure in case of elevated intraocular pressure.
5. When used in osseous arthritis, It can be combined with prednisone dragon. This can relieve pain, and recover joint function.
6. When it used in eye surgery, we should be closely monitoring intraoperative and postoperative intraocular pressure.
About the information about the physical and chemical properties pharmacological action, pharmacokinetics, clinical application usage and dosage of sodium hyaluronate in ophthalmology by chemical