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Shark Chondroitin Sulfate Improvement In Functionality For Patients With Arthritis

Shark Chondroitin Sulfate Improvement In Functionality For Patients With Arthritis

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Shark Chondroitin Sulfate Improvement in Functionality for Patients with Arthritis

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Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. A chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities. Chondroitin sulfate is an important structural component of cartilage and provides much of its resistance to compression. Along with glucosamine, chondroitin sulfate has become a widely used dietary supplement for treatment of osteoarthritis.

Medical use

Although chondroitin is used in dietary supplements as an alternative medicine to treat osteoarthritis and also approved and regulated as a symptomatic slow-acting drug for this disease (SYSADOA) in Europe and some other countries, it is technically neither a medicine nor a disease-modifying treatment. See Clinical effects below. It is commonly sold together with glucosamine. Chondroitin and glucosamine are also used in veterinary medicine. Formulated with collagen and wound dressing matrix, one product that uses chondroitin sulfate is the veterinary wound gel Chondroprotec, which is applied over scrapes, burns, and lesions and serves to keep the wound moist and promote healing.

Chondroitin, along with commonly used glucosamine, should not be used to treat patients who have symptomatic osteoarthritis of the knee as evidence shows that these treatments fail to provide relief for that condition.


Uses of Chondroitin Sulfate

The most common uses for chondroitin sulfate in health supplements is for joint support and mobility. Additional uses include the support of bones, bladder and skin.


Chondroitin sulfate is considered a promising treatment for osteoarthritis. It is most often used to treat osteoarthritis of the finger, knee, hip joints, low back, and facial joints. Research has mostly focused on knee osteoarthritis, with fewer studies conducted on other joints. Clinical trials suggest that chondroitin may have significant effects when compared to placebo. Chondroitin is a slow-acting medication that may lead to reduced doses of other drugs. However, adequate assessment of long-term safety, side effects, and effectiveness is lacking.

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Technical Standards

Test Items



Off-White Powder

Optical Rotation

(–12°) ~ (-20°)



Loss on drying




Residue on Ignition






PH (1% Solution)

5.5 – 7.5

Heavy Metals




Total plate count


Yeast & Mold







USP standard

Shelf Life

Three Years